Custom products

Unlock the potential of your research with our specialized service for the enzymatic synthesis of nucleoside 5'-triphosphates. Leveraging decades of expertise, we offer a streamlined and modular approach to convert your modified nucleoside substrates into high-purity triphosphates. Whether you're working on RNA biology, drug development, or synthetic biology, our service provides a fast, reliable, and cost-effective solution tailored to your specific needs.

• 20 - 30 working days turnaround time
• 0.5 - 2 µmol production
• Over 90 % optical purity guaranteed
• PROMO OFFER: The enzyme screening is free of charge!

Our process is designed with your research efficiency in mind. From submission to delivery, we handle every step with precision and care.

1. Initial enzyme screening:
   Send us your modified nucleoside substrate, and our team will conduct an initial screening using our extensive enzyme library to assess the feasibility and optimize the production process. If the substrate molecule is commercially available, we can also order it directly from a retailer. The initial screening will be skipped and will not be billed if the desired product has already been produced by us before.
   
2. Enzymatic synthesis:
   Using our proprietary enzymatic methods, we convert your nucleoside into a high-purity triphosphate, ensuring maximum yield and consistency.
   
3. Purification & Quality Control:
   Each batch undergoes rigorous purification and quality control to ensure over 90% purity (HPLC-DAD), providing you with reliable and reproducible results.
   
4. Delivery:
   Within 20-30 working days, receive your custom nucleoside triphosphate, ready to accelerate your research.

Our custom nucleoside triphosphate production service is ideal for a wide range of applications, including but not limited to:

• RNA Biology: Synthesize modified nucleotides for RNA research and development.
• Drug Discovery: Generate high-purity triphosphates for the development of novel therapeutics.
• Synthetic Biology: Create custom nucleotides for synthetic biology projects, enabling advanced genetic engineering.

Ready to accelerate your research with custom nucleoside triphosphates? Contact us today to discuss your project and receive a personalized quote.

Have questions? We have answers. Here are some of the most common inquiries about our custom nucleoside triphosphate production service: 

What is the typical turnaround time for production?

Our standard turnaround time is 20-30 working days, depending on the complexity of your nucleoside substrate. Please be aware that we can only start producing once we have received your nucleoside substrate.

How will the product be delivered?

By default we deliver nucleotide products as sodium salts in neutralized or slightly basic solutions, as this generally provides best stability. The product concentration can be tailored to your needs. The shipment of dry powder is possible but may require additional stability tests.

What purity level can I expect?

We guarantee an optical purity level of over 90% for all nucleoside triphosphates produced. Purity is determined by HPLC-DAD.

How much nucleoside triphosphate will I receive?

By default we offer production in the scale of 0.5-2 µmol final product. If you require more just contact us, but be aware that production time may be higher.

Can you work with any nucleoside substrate?

We can work with a wide range of modified nucleosides. The more we know about the substance the better we can plan the production, but working with non-disclosed structures is also possible. Contact us to discuss the specifics of your project.

How much does it cost?

Our service is competitively priced, but depends highly on the respective nucleoside substrate and its feasability in biocatalytic conversion. 

We will first perform an enzyme screening and initial process evaluation that is fixed at a price of 590 € currently free of charge! After that we can assess the production cost for you. You will have the option to accept or refuse the offer at this point.

Screening and process evaluation will be skipped and will not be billed if the desired product has already been produced by us before.

The cost of the final product may vary depending on: